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Some individuals have both antigens (blood group AB) or neither antigen (blood group O).In addition to the A and B antigens, an individual may possess the Rh antigen.

This is manifest as an increase in the number of reticulocytes in the peripheral blood.These immature erythrocytes are released from the bone marrow into the blood where they quickly mature.Thus, as erythrocyte production in the bone marrow increases, so does the number of reticulocytes in the blood.Examination of the buffy coat reveals five different kinds of leukocytes, classified according to their staining properties.These five kinds are further classified according to whether or not they contain conspicuous cytoplasmic granules.

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